Hot Springs Cyanobacteria Endowed with Biological Activities for Cosmetic Applications: Evaluation of On-Site Collected Communities and Isolated Strains

Microbial communities growing around hot springs (bioglea), of which cyanobacteria are the main components, contribute to beneficial properties thermal muds and often enter cosmetic treatment products. Bioglea is obtainable via alternative approaches harvesting from nature: direct cultivation whole isolation isolated strains. Cultivation represents a step towards industrial production, guaranteeing higher availability, quality safety. In this work, biochemical composition natural cultivated bioglea collected in different cyanobacterial strains thereof was analysed. Lipophilic hydrophilic extracts were tested for antimicrobial radical scavenging activities toxicity against Artemia salina. Higher activity found lipophilic than opposite isolates’ extracts. Thermal water also showed some activity. No observed. positively correlated with carotenoids (lipophilic extracts) phycobiliproteins (hydrophilic extracts). correlation observed at 10 L scale Chroococcidiopsis BIOG3 evidenced bioactivity changes growth phase life cycle stage. From comparison, potential over single cultivation; however, further investigations should elucidate full by combining them into synthetic simplify production standardisation.